PHARMACOLOGY

Which of the following drug is administered intrathecally to treat fungal meningitis
a)Azoles
b)Amphotericin B
c)Echinocandins
d)Flucytosine
e)Griseofulvin

Which of the following antifungal drug is used to treat onychomycosis
a)Ketoconazole
b)Itraconazole
c)Voriconazole
d)Posiconazole
e)Amphotericin B

Which of the following durg causes visual disturbance
a)Posiconazole
b)Voriconazole
c)Ketoconazole
d)Caspofungin
e)Amphotericin B

Which of the following drug is Fungistatic
a)Terbinafine
b)Griseofulvin
c)Caspofungin
d)Amphotericin B
e)Nystatin

Which is the drug of choice if the patient is suffering from persistant lung lesion or disseminated disease caused by coccidoided immitis
a)Amphotericin B
b)Fluconazole
c)Ketoconazole
c)Micofungin
d)Terbinafine

Drug of choice for asymptomatic intsetinal amebiasis
a)Metronidazole
b)Paramomycin
c)Iodoquinol
d)Tinidazole
e)Diloxinade furaote

Drug of choice for extra luminal amebiasis
a)Metronidazole
b)Chloroquine
c)Diloxinade furaote
d)Paromomycin
e)emetine

which of the following drug shows thyroid enlargement, neurotoxic effect, visual disturbance as a side effect
a)Emetine
b)Iodoquinol
c)Metronidazole
d)Tinidazole
e)Paromomycin

Identify the drug which is active against metronidazole resistant protooal strains
a)Emetine
b)Nitazoxanide
c)Diloxinade furaote
d)Paramomycin
e)Primaquine

Which of the following drug should be given later to eradicate shizonts and latent hypnozites in pateints liver
a)Amodiaquine
b)Halofantrine
c)Primaquine
d)Quinine
e)Sulfadoxine

Identify the durg which is used as a choice for non falciparum and falciparum sensitive malaria and can also be used as for the treatment of rheumatoid arthritis
a)Chloroquine
b)Mefloquine
c)Primaquine
d)Proguanil

which of the following drug perform its action by acting on gametocide
a)Primaquine
b)Proguanil
c)Artemether
d)Pyrimethamine

Fansidar used for treatment of choloroquine resistant strains of falciparum is  combination of
a)Proguanil & atovoqine
b)Pyremethamine & atovoquine
c)Proguanil & sulfadoxine
d)Pyremethamine & atovoquine

Most potent H2 receptor antagonist
a)Cimetdine
b)Famotidne
c)Ranitidne
d)Nizatidine

Drug use to treat chemotherapy induced nausea and vomiting
a)scopolamine
b)Ondensatron
c)Phenothiazines
d)Misoprostol
e)Sucralfate

Which of th following drug is drug of choice to treat filliarial worms infection
a)Albendazole
b)Mebendazole
c)Diethylcarbamazine
d)Peperazine

which of the following drug intensifies gaba mediated transmission in nematodes
a)Oxamniquine
b)Albendazole
c)Ivermectin
d)Peperazine

Which of the following drug is effective against schistoma hematobium
a)Oxamniquine
b)Metronidaole
c)Niclosamide
d)Praziquantel

Which of the follwoing can be use in the treatment of arthrsclerotic vascular disease
a)HMG-COA reductase inhibitor
b)Resins
c)Ezetimibe
d)Niacin
e)Firbates

A 5 year old boy was diagnosed as having intestinal infection with pinworm he should be treated with
a)Ivermectin
b)Mebendazole
c)Mefloquine
d)Praziquantel
e)Quinine

Cell wall inhibitors
Psuedomembranous collitus is common adverse effect of
a)oxacillin
b)ampicillin
c)methicillin
d)pipercillin

penicillins
antipsuedomona penicilins are
a)pipercillin
b)ticarcillin
c)oxacilin
d)penicllin g

cell wall inhibitors
cephalosporine which excrete in bile is
a)cifepime
b)cefaparazone
c)ceftraixone
d)cefamandole

cell wall inhibitors
Red man syndrome is common side effect of
a)vancomycin
b)streptomycin
c)fosfomycin
d)bacitracin

cholinomemitic drugs
Which of the following is direct-acting cholinomimetic that is lipid soluble and is used to facilitate smoking cessation.
a)acetylcholine
b)bethanechol
c)neostigmine
d)physostimine
e)varenicline

drug metabolism
Drug metabolism in humans usually results in a product that is.
a)less lipid soluble than the original drug
b)more likely to distribute intracellularly
c)more likely to be reabsorbed by kidney tubules
d)more lipid soluble than the original drug
e)less water soluble than tha original drug.

Anti hypertensive drugs
A 32 year old women with hypertension wishes to become pregnant. Her physician informs her that she will have to switch to another antihypertensive drug. Which of the following drug is completely contraindicated in pregnancy.

a)atenolol
b)captopril
c)methyldopa
d)prazosin
e)propanolol

w/c of the following drug is absolutely contraindicated in pregnancy
a) Atenolol
b) captopril
c) Methyldopa
d) Prazosin

MOA of hydrochlorothiazide (diuretics) is
a)Block na/k/cl transporter
b)alpha2 agonist
c)Block Na/cl transporter

Which of the following drug block L-type calcium channel
a)Diazoxide
b)verapamil
c)Dilitiazem
d)B and c
e)none of the above

W/c drug is the renin inhibitor
a)Aliskerin
b)captopril
c)Losartan
d)All

W/c of the nitrate Has the shortest duration
a)Isosorbide dinitrate
b) nitroglycerin,sublingual
c) Nitroglycerine,oral
d)Amyl nitrite

Headache is the most common side effect of which drug used in angina
a)Verapamil
b)Propranol
d)Nitroglycerin
d)Atenolol

MOA of digoxin is :
a)Na channel block
b)inhibit  Na/k/ATpase pump
c)Calcium channel blocker
d)Ace inhibitor

Dobutamine is a
a)Beta 1 agonist
b)beta 2 antagonist
c)Beta non selective agonist
d)None